This Post is adapted from the Canadian Pharmacists Association (CPhA) Drug Monograph: Biphosphonates Product Summary Pharmacology Bisphosphonates (previously called diphosphonates) are stable analogues of pyrophosphate. After binding to bone surfaces, they slow the formation of hydroxyapatite crystals and delay their aggregation into large clusters. They also interfere with the resorptive action and promote apoptosis (programmed […]
This summary of evidence is based on the Annals of Internal Medicine Supplement (Ann Intern Med. 2013;158:365-368) and on the report by the Agency for Healthcare Research and Quality: Making Health Care Safer II: An Updated Critical Analysis of the Evidence for Patient Safety Practices Annals of Internal Medicine Supplement Full Report (PDF) Structured Abstract Study […]
This question was submitted by a general dentist: “How can we deliver effective oral hygiene instruction to children with autism?” Dr. John O’Keefe, Director of Knowledge Networks at CDA interviewed Dr. Clive Friedman, past President of the International Association for Disability and Oral Health (IADH) and current member of IADH Education Committee Understanding your patient […]
This Medical Condition Consult is presented by the JCDA Oasis Team. It is also available through the Oasis Help system Our sincere thanks go to the MDs who developed and reviewed this medical consult. Hemophilia is a hereditary bleeding disorder caused by low factor VIII coagulant activity (hemophilia A) or low levels of factor IX […]
This Post is adapted from the Canadian Pharmacists Association (CPhA) Drug Monograph: Barbiturates Barbiturates Product Summary Information Barbiturates are nonselective central nervous system (CNS) depressants, capable of producing all degrees of depression from mild sedation and hypnosis to general anesthesia, deep coma and death. The extent of CNS depression varies with the route of […]
This post is adapted from the Canadian Pharmacists Association (CPhA) Therapeutic Choices on Neurologic Disorders: Acute Pain Pain is one of the commonest symptoms. It needs to be recognized, assessed for cause and treated appropriately as soon as possible. The absence of treatment can lead to physiological and psychological adverse effects. Treatment should be tailored to […]
This Post is adapted from the Canadian Pharmacists Association (CPhA) Drug Monograph: ACE Inhibitors ACE Inhibitors Product Summary Information Drug Administration Dosage Form Strength Benazepril Oral Tablet 5 mg, 10 mg, 20 mg Captopril Oral Tablet 6.25 mg, 12.5 mg, 25 mg, 50 mg, 100 mg Cilazapril Oral Tablet 1 mg, 2.5 mg, 5 mg […]
This summary is based on the Rapid Response Report developed by the Canadian Agency for Drugs and Technologies in Health: Botulinum Toxin A for the treatment of trigeminal neuralgia and temporomandibular joint dysfunction: a review of the clinical effectiveness Full Report (PDF) CONTEXT Temporomandibular joint dysfunction (TMD) is a musculoskeletal and rheumatologic disorder of the temporomandibular joint, […]