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Dental biofilm of symptomatic COVID-19 patients shelters SARS-CoV-2

SARS-CoV-2 RNA has been recovered from different sites in the human body, including the mouth. The present study aimed to investigate the presence of SARS-CoV-2 RNA in the dental biofilm of symptomatic patients who tested positive in nasopharyngeal and oropharyngeal (NASO/ORO) samples.

An observational clinical study of individuals with flu-like symptoms was conducted between July and September 2020. Dental biofilm (BIO) samples were collected and analyzed using real-time quantitative polymerase chain reaction (RT-qPCR)\ to determine the virus's presence. Seventy participants tested positive for SARS-CoV-2 RNA in NASO/ORO samples and were included in the study. Among them, 13 tested positive in BIO samples. BIO-positive participants showed a higher virus load in NASO/ORO samples than those testing negative.

Dental biofilms from symptomatic COVID-19 patients harbour SARS-CoV-2 RNA and might be a potential reservoir with an essential role in COVID-19 transmission.

Dr. Sabrina Carvalho Gomes speaks about the study and its findings in this conversation with Chiraz Guessaier, from the CDA Oasis team.

We hope you find the conversation useful. We welcome your thoughts, questions and/or suggestions about this post and other topics. Leave a comment in the box below or send us your feedback by email.

Until next time!
CDA Oasis Team


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