What is the effect of preventive use of nonsteroidal anti-inflammatory drugs on sensitivity after dental bleaching? A systematic review and meta-analysis

This summary is based on the article published in the Journal of the American Dental Association: Effect of preventive use of nonsteroidal anti-inflammatory drugs on sensitivity after dental bleaching. A systematic review and meta-analysis (February 2015)

• André Luis Faria-e-Silva, DDS, MD, PhD
• Flávia Pardo Salata Nahsan, DDS, MD, PhD
• Micaelle Tenório Guedes Fernandes, DDS
• Paulo Ricardo Saquete Martins-Filho, DDS, MD, PhD

Context

• Tooth sensitivity associated with bleaching remains a challenge for clinicians.
• Inflammatory mediators released by the penetration of bleaching agents into dental tissues can sensitize nociceptors, leading to tooth sensitivity.

Purpose of the Review

To analyze the effect of preventive analgesia with nonsteroidal anti-inflammatory drugs (NSAIDs) on tooth sensitivity associated with in-office bleaching.

Key Findings

• Preventive analgesia with NSAIDs did not have a significant effect on the risk of sensitivity after dental bleaching or on the levels of sensitivity reported by patients.
• There is insufficient evidence about the use of NSAIDs to prevent tooth sensitivity caused by in-office bleaching procedures.

References

List of references included in the review (PDF)