Pharmacological Reversal Agents in Dental Practice: Keys to Patient Safety
I had the pleasure to host Dr. Mark Donaldson to speak about the important reversing drugs that are found in the dental emergency kit. Mark goes into detail addressing 6 reversal agents: Naloxone, Flumazenil, Epinephrine, Diphenhydramine, Phentolamine, and Atropine.
Chiraz Guessaier, CDA Oasis Manager
- Though uncommon, medical emergencies in the dental office are harrowing occurrences that can be the result of adverse drug reactions.
- Pharmacological antagonists have been developed for administration as reversal agents in emergency situations in which patients may have an untoward effect, typically caused by too much medication.
- Dental practitioners should be familiar with these agents to keep patients safe and help mitigate drug-induced medical emergencies.
- Outside of emergency situations, the pharmacological antagonist phentolamine has been developed to reverse the effects of the vasoconstrictor in dental local anesthesia preparations when the effects of the agonist medication are no longer required.
- Such newer reversal agents are being considered for more routine use once the dental procedure is complete.