Home » Supporting Your Practice » Medicine » Pharmacology (page 5)

Pharmacology

What are the trends in high-dose opioid prescription in Canada?

This summaary is based on the article published in Canadian Family Physician: Trends in high-dose opioid prescribing in Canada (September 2014) Tara Gomes, Muhammad M. Mamdani,  J. Michael Paterson, Irfan A. Dhalla, David N. Juurlink    Context Canada and the United States have the highest levels of prescription opioid consumption in the world, and the use of these medications continues to increase dramatically across North America. (1–5) Until recently, clinical practice guidelines and product monographs provided no recommended maximum dose, and opioids were marketed as having no upper dose threshold, despite scant evidence of safety or effectiveness at high doses, particularly in patients ...

Read More »

Why are Lanolin-based creams and ointments preferred over petroleum-based products for moisturizing and protective properties?

This question was submitted by a general dentist: Why are Lanolin-based creams and ointments preferred over petroleum-based products for moisturizing and protective properties? Dr. Carol Janik and Caroline Fulop provided this initial response.  The key difference between lanolin and petroleum-based products lie in their properties. Lanolin is classified as an emollient whereas Petrolatum is classified as an occlusive. Emollients are oils and lipids that spread easily on the skin and provide partial occlusion resulting in hydration (Rawlings et al., 2004). It has been shown that emollient lipids resemble those naturally found on the skin and have been shown to improve the ...

Read More »

Does the use of antibiotics reduce the frequency of implant failure and post-operative infection?

This summary is based on the article published in the International Journal of Oral and Maxillofacial Surgery: Do antibiotics decrease implant failure and postoperative infections? A systematic review and meta-analysis (January 2014) J. Ata-Ali, F. Ata-Ali, F. Ata-Ali       Context Dental implants are an effective, safe and predictable solution for those who have lost a tooth or teeth due to dental caries, periodontal disease, injury, or other reasons.(1) It is believed that a certain number of early dental implant losses are due to bacterial contamination at implant insertion.(2) It is still debated whether early dental implant failure and ...

Read More »

Does adrenaline in local anesthetics increase or decrease bleeding at the surgical site?

This question was submitted by a general dentist: Does adrenaline in local anesthetics increase or decrease bleeding at the surgical site? Dr. Mark Donaldson, in collaboration with Dr. Suham Alexander, Oasis Discussions Clinical Editor, provided this initial response.  Dr. Mark Donaldson is Director of Pharmaceutical Services at the Kalispell Regional Medical Center, Clinical Professor in the Department of Pharmacy at the University of Montana, and Clinical Associate Professor in the School of Dentistry at the Oregon Health and Sciences University Local Anesthetic Composition Most local anesthetic cartridges contain the following ingredients: Local anesthetic drug Vasoconstrictor Preservative, if contains vasoconstrictor Sodium chloride Distilled ...

Read More »

What are some of the immunological diseases encountered in dental practice?

This summary is based on the article published in the British Dental Journal: General medicine and surgery for dental practitioners: part 5. Immunological disease and dental practice (August 2014) M. Greenwood, J. G. Meechan and C. Stroud   Context At some stage in clinical practice all dental practitioners will encounter patients with disorders of the immune system. It is therefore important that dental practitioners are aware of the potential implications for safe practice. Purpose of the Paper Provides an overview of clinical immunology and how it interfaces with dentistry. Highlights signs of possible immunodeficiency. Discusses oral conditions that may be ...

Read More »

Efudex: Should you be prescribing it?

This question was submitted by a general dentist:  When discussing sun damage to lips, a couple of patients told me that they were prescribed Efudex by their physician. There is apparently no follow-up by the physician and no indication to the patients as to what the desired outcome of the said treatment should be. Should dentists be prescribing this and what would the appropriate follow-up and regimen be for this chemotherapeutic agent?     Dr. Mark Donaldson provided this quick initial response in collaboration with Dr. Suham Alexander, Oasis Clinical Editor Dr. Mark Donaldson is Director of Pharmaceutical Services at ...

Read More »

Anaphylaxis: an update for dental practitioners

This summary is based on the article published in the Australian Dental Journal: Anaphylaxis: an update for dental practitioners (June 2014)

Read More »

How are bisphosphonates used in children? Review of the literature and guidelines for dental management

This summary is based on the article published in the Australian Dental Journal: The use of bisphosphonates in children: review of the literature and guidelines for dental management (March 2014)

Read More »