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Pharmacology

Oasis Patient Resource: Dry Mouth

The Oasis Patient Resource is a series of tools that help dentists explain basic dental concepts and procedures to their patients. This video and additional materials are provided to dentists to use for patient information. If you are interested in using the video in your own practice, please email us at oasisdiscussions@cda-adc.ca and we will gladly provide you with the original Powerpoint presentation as well as the video file. You will then be able to customize it with your own logo and office information.  Download this Oasis Patient Resource: Dry Mouth (PDF)  Download the original Dry Mouth Pamphlet (PDF) Watch the video  Please note that you ...

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Dealing with systemic diseases in the elderly patient

This summary is based on the article published in Dental Clinics of North America: Systemic Diseases and Oral Health (October 2014) Mary Tavares, DMD, MPH; Kari A. Lindefjeld Calabi, DMD; Laura San Martin, DDS, PhD, MDPH           Context Inflammation has been recognized as the key factor that connects oral diseases and systemic chronic diseases. 1 Chronic diseases are defined as long-lasting illnesses, with duration of more than 3 months that affect a person’s life and require constant medical treatment. The complexity of dental treatment in the elderly is greater because of the effects of these chronic diseases, ...

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What are the oral implications of polypharmacy in the elderly?

This summary is based on the article published in Dental Clinics of North America: Oral Implications of Polypharmacy in the Elderly (October 2014) Mabi L. Singh, DMD, MS; Athena Papas, DMD, PhD       Context There are age-related changes in the systems of the body, which alter the pharmacokinetics and pharmacodynamics of medications and make the elderly more vulnerable to adverse events. A major side effects of medications is the qualitative and quantitative change the cause in saliva (salivary hypofunction), by their anticholinergic effects. With salivary hypofunction, a plethora of complications arise, resulting in decreased quality of life in the ...

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Is octenidine hydrochloride available and/or recommended as an oral rinse agent?

This question was submtted by general dentist: Since Octenidine Hydrochloride seems better than Chlorhexidine, is it available and/or recommended as an oral rinse agent?  Under what name can it be purchased? Drs. Archie McNicol and Suham Alexander provided this quick initial response.   Antiseptic mouth rinses are used clinically to improve dental health and/or to prevent infections arising from oral pathogens. Antimicrobial mouth rinses target predominantly Streptococcus mutans.  Octenidine hydrochloride (Octenisept) belongs to a class of chemicals called bispyridinamines and was initially developed for use as a topical antimicrobial agent. It is capable of forming complexes and adhering to whole cells ...

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What is the placebo effect on burning mouth syndrome? A review

This summary is based on the article published in Oral Diseases: Placebo effect in burning mouth syndrome: a systematic review (April 2014) M Kuten-Shorrer, JM Kelley, ST Sonis, NS Treister     Context Burning mouth syndrome (BMS), also referred to as stomatodynia, is a chronic pain condition that manifests as a burning dysesthesia in the oral cavity, generally localized to the tongue, but that also frequently affects the inner aspect of the lips and the anterior hard palate. 1 BMS is defined by the absence of any local or systemic causes such as candidiasis, hyposalivation, nutritional deficiencies, or uncontrolled diabetes. ...

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Audio Interview: Researchers at the University of Calgary unlock a new mechanism in pain management

Dr. Chiraz Guessaier, CDA Oasis Project Manager, spoke with Dr. Gerald Zamponi, Neuroscientist, Professor, and Senior Associate Dean of Research in the Faculty of Medicine at the University of Calgary. Dr. Zamponi and his team unlocked a new mechanism in pain management by means of which chronic pain can be reversed.       Listen to the audio interview http://www.oasisdiscussions.ca/wp-content/uploads/2014/09/Zamponi_Original.mp3   View Dr. Gerald Zamponi profile Visit the Hotchkiss Brain Institute website  

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What are the trends in high-dose opioid prescription in Canada?

This summaary is based on the article published in Canadian Family Physician: Trends in high-dose opioid prescribing in Canada (September 2014) Tara Gomes, Muhammad M. Mamdani,  J. Michael Paterson, Irfan A. Dhalla, David N. Juurlink    Context Canada and the United States have the highest levels of prescription opioid consumption in the world, and the use of these medications continues to increase dramatically across North America. (1–5) Until recently, clinical practice guidelines and product monographs provided no recommended maximum dose, and opioids were marketed as having no upper dose threshold, despite scant evidence of safety or effectiveness at high doses, particularly in patients ...

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Why are Lanolin-based creams and ointments preferred over petroleum-based products for moisturizing and protective properties?

This question was submitted by a general dentist: Why are Lanolin-based creams and ointments preferred over petroleum-based products for moisturizing and protective properties? Dr. Carol Janik and Caroline Fulop provided this initial response.  The key difference between lanolin and petroleum-based products lie in their properties. Lanolin is classified as an emollient whereas Petrolatum is classified as an occlusive. Emollients are oils and lipids that spread easily on the skin and provide partial occlusion resulting in hydration (Rawlings et al., 2004). It has been shown that emollient lipids resemble those naturally found on the skin and have been shown to improve the ...

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