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Pharmacology

Case Conference: How would you treat this 73-year old patient on chemotherapy?

Dr. Linda Lee presents the case of a 73-year old female patient who is undergoing chemotherapy. Dr. Linda Lee DDS, MSc. Dipl. ABOP, FRCD(C), Oral Pathology/Medicine     Dr. Lee is Associate Professor, Faculty of Dentistry, University of Toronto Staff Dentist, Princess Margaret Cancer Centre, University Health Network. Dr. Lee received her DDS degree in 1977 from the University of Toronto and her Certificate in Oral Pathology, Indiana University School of Dentistry Master of Science, Indiana University.       Watch the case presentation   We welcome your input about this topic. You have the option to remain anonymous in leaving your feedback. Please note ...

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Case Conference: Where Do Opioids fit in the Management of Acute Post-Surgical Pain?

Drs. Chris Lee and Brian Cairns spoke with Dr. John O’Keefe about the management of acute post-surgical pain and when and how should opioids be used in such situations. Dr. Chris Lee is Assistant Professor/Director, Department of Dental Clinical Sciences, Divisions of Comprehensive Care, Preventative Dentistry & Oral Health Promotion, General Practice Residency. He is also Director, Emergency Recall Clinic, Clinics & Building Services, and General Dentist, Dalhousie Dentistry Faculty Practice. Dr. Brian Cairns is Professor in the Faculty of Pharmaceutical Sciences at the University of British Columbia.    Part 2 of the Conversation: Questions & Answers: Where Do Opioids fit in the Management of Acute ...

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Update on medical emergencies in dental practice and on local anesthesia: key messages from Dr. David Isen

                    On April 10, 2014, Dr. David Isen delivered an all-day continuing education course on medical emergencies in dental practice, and on advanced local anesthesia for dentists for the Ottawa Dental Society. At the end of the course, Dr. Isen briefly summarized for me the key takeaway messages that he communicated during his course. That summary is captured in the video embedded in this post (the video is just over 2 minutes long). The course was very well attended and the feedback from attendees was very positive. Dr. Isen is a ...

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How justified are dentists in using antibiotics? A review

This summary is based on the article published in the International Dental Journal: Antibiotics in dental practice: how justified are we (February 2015) Sukhvinder S. Oberoi, Chandan Dhingra, Gaurav Sharma, Divesh Sardana Courtesy of Wiley Publishing, you can access the full-text article for the next 3 months here (PDF) Context Antibiotics are prescribed by dentists in dental practice, during dental treatment as well as for prevention of infection. Indications for the use of systemic antibiotics in dentistry are limited because most dental and periodontal diseases are best managed by operative intervention and oral hygiene measures. The use of antibiotics in ...

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What are the most common adverse drug reactions in dental practice?

This summary is based on the article published in Anesthesia Progress: Adverse Drug Reactions in Dental Practice (Spring 2014) Daniel E. Becker, DDS Context Adverse reactions may occur with any of the medications prescribed or administered in dental practice. Most of these reactions are somewhat predictable based on the pharmacodynamic properties of the drug. Others, such as allergic and pseudoallergic reactions, are less common and unrelated to normal drug action. Purpose of the Article To review the most common adverse reactions that are unrelated to drug allergy. Key Messages Sedatives, Opioids, and General Anesthetics Respiratory depression is the most significant ...

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Conversation Opener: Antibiotics prescribing patterns among health professionals in B.C.

Dr. David Patrick spoke with Dr. John O’Keefe about the prescribing patterns of antibiotics among health professionals in B.C. Dr. David Patrick is a medical doctor, Associate professor in the Division of infectious diseases, School of Population and Public Health at UBC, and Director of Epidemiology Services at the BC Center for Disease Control. To contact Dr. David Patrick by email: david.patrick@ubc.ca  Watch the video Additional resource  Fawziah M, George D, Chong M, Sutherland S, Patrick DM. Antibiotic prescribing by dentists has increased: why?. J Am Dent Assoc. 2016 Feb 5. doi: http://dx.doi.org/10.1016/j.adaj.2015.12.014 [Epub ahead of print]

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What are the expected benefits and potential harms of bisphosphonates for the treatment of osteoporosis?

This summary is based on the article published in the Canadian Family Physician journal: Bisphosphonates for treatment of osteoporosis. Expected benefits, potential harms, and drug holidays. A Clinical review. (April 2014) Jacques P. Brown MD; Suzanne Morin MD MSc; William Leslie MD; Alexandra Papaioannou MD; Angela M. Cheung MD PhD; Kenneth S. Davison PhD; David Goltzman MD; David Arthur Hanley MD; Anthony Hodsman MD; Robert Josse MD; Algis Jovaisas MD; Angela Juby MD; Stephanie Kaiser MD; Andrew Karaplis MD; David Kendler MD; Aliya Khan MD; Daniel Ngui MD; Wojciech Olszynski MD PhD; Louis-Georges Ste-Marie MD; and Jonathan Adachi MD Context  ...

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Does the sugar found in medications increase the risk of caries?

This summary is based on the article published in the Journal of the American Dental Association: Sugar content, cariogenicity, and dental concerns with commonly used medications (February 2015) Mark Donaldson, BSP, RPH, PharmD, FASHP, FACHE Jason H. Goodchild, DMD Joel B. Epstein, DMD, MSD, FRCD(C), FDS, RCS(Edin) Courtesy of the American Dental Association, you can access the full-text article for the next 3 months here (PDF) Context Oral adverse events such as cariogenicity are often overlooked as drug-associated effects because the sugar content of many medications may be negligible compared with the patients’ overall dietary intake of sugar. There are, ...

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