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Pharmacology

What do you really need to know about bisphosphonates?

Once again, I had the pleasure to welcome Dr. Mark Donaldson, expert pharmacologist and Senior Executive Director at Vizient Pharmacy Advisory Solutions. As we reach five decades of clinical use of bisphosphonates, and coinciding with the publication of a recent article by Dr. Mark Donaldson and his colleague Dr. Jason Goodchild, we thought it pertinent to bring you the latest related research and their use in dentistry. Dr. Mark Donaldson is a Clinical Professor in the Department of Pharmacy at the University of Montana in Missoula, Clinical Associate Professor in the School of Dentistry at the Oregon Health & Sciences ...

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Pattern of Opioid Analgesic Prescription for Adults by Dentists in Nova Scotia

Colleagues, I have just come across this paper that was recently published by Canadian authors in the journal JDR Clinical & Translational Research. I thought it would interest you, so I present below the publicly-available abstract along with a link to the journal, in the event that you wish to purchase the article and/or familiarize yourself with the publication. Dr. Jocelyne Feine of McGill University is editor in chief of the journal. All the best, John   Pattern of Opioid Analgesic Prescription for Adults by Dentists in Nova Scotia, Canada K.O. Jimoh, D.C. Matthews, M. Brillant, and I. Sketris JDR ...

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Could the prescription you write put you in legal jeopardy?

It was with much pleasure that I hosted once again Dr. Mark  Donaldson on CDA Oasis. Dr. Donaldson has been kind and most generous in sharing his recent publications as well as his expertise on very important pharmacological topics. Today he speaks to our audience about the liabilities dentists might incur when prescribing opioids in light opioid crisis experienced in North America.  Dr. Donaldson is senior executive director at Vizient Pharmacy Advisory Solutions as well as clinical professor in the Skaggs School of Pharmacy at the University of Montana. I hope you enjoy and benefit from the conversation. Always remember that ...

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What are the adverse effects and complications of local anesthetics?

Highlights In this short presentation, Dr. Aviv Ouanounou discusses the possible adverse effects of administering local anesthetics. Psychogenic reactions include most commonly syncope, as well as hyperventilation, nausea, and changes in heart rate and blood pressure. Allergic reactions are usually very rare and if they occur, they are usually related to the ester type of local anesthetics. Paresthesia is a complication that may occur following the administration of local anesthesia. It usually resolves within 6-8 weeks. It is thought that 4% solutions of local anesthetic may have higher risk of causing paresthesia. Hematomas are also another complication. They will commonly ...

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The Prevention and Management of Medication Related Osteonecrosis of the Jaw: Two Cases

Today, we bring you two interesting complex cases that were treated by Dr. Erin Watson, general dentist practicing out of Princess Margaret Cancer Center, and Dr. Irwin Golosky, Endodontist in Toronto.  Both cases deal with patients who are at higher risk for medication related osteonecrosis of the jaw (MRONJ). Educational information is also presented to frame the situation and provide relevance to the general dentist. In cases where it is possible to prevent MRONJ, treatment is somewhat straightforward. However, in other cases where there is already a risk of MRONJ, treatment is challenging and requires the tight collaboration of a ...

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Which Medications Induce Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea? A Systematic Review

Highlights Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation of oral dryness), and subjective sialorrhea cause significant morbidity and impair quality of life. However, no evidence-based lists of the medications that cause these disorders exist. The objective was to compile a list of medications affecting salivary gland function and inducing xerostomia or subjective sialorrhea. Data Sources Electronic databases were searched for relevant articles published until June 2013. Of 3867 screened records, 269 had an acceptable degree of relevance, quality of methodology, and strength of evidence. We found 56 chemical substances with a higher level of evidence and 50 with a moderate ...

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Fentanyl: What you Should Know

Dr. JoonYoung Ji returns on Oasis Discussions to speak about Fentanyl, a potent opioid that has surfaced in recent times as an abused substance responsible for many overdoses and deaths. Dr. Ji explains what Fentanyl is and why it would be found in a dental practice if ever.  We hope you find the conversation valuable and that you share your feedback with us on Oasis Discussions or through oasisdiscussions@cda-adc.ca. Bookmark our page and visit us frequently to keep up to date with the latest in the world of dentistry! Chiraz Guessaier, CDA Oasis Manager Highlights Fentanyl and carfentanyl have recently been in the ...

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Using Antibiotics Wisely to Combat Rising Drug Resistance

November 13 to 19, 2017 is World Antibiotic Awareness week. I have invited Dr. Shelita Dattani, Director, Practice Development and Knowledge Translation at the Canadian Pharmacists Association, to speak to our audience about antimicrobial resistance and stewardship. The issue is at the forefront of the World Health Organization list of priorities as rising resistance becomes gradually a global phenomenon.  Dr. Dattani spoke about how dentists and pharmacists are playing a crucial role in helping solve this issue.  We hope you find the interview informative and join our conversation. You can always share your feedback with us on Oasis Discussions or through oasisdiscussions@cda-adc.ca. Bookmark our page ...

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