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Medicine

What is Hypophosphatasia (HPP)?

Highlights In the first segment of a 4-part series, Dr. Marc McKee introduces Oasis Discussions followers to a soft bone disease which also has a significant dental impact. Hypophosphatasia (HPP) is a very rare disease that has a prevalence of  approximately 1:100,000 live births.  Much progress has been made in recent years in understanding HPP, and in treating patients with this condition. HPP is a disease which negatively affects mineralization due to an increase in inhibitory pyrophosphate levels caused by decreased activity of an enzyme called tissue non-specific alkaline phosphatase (TNAP, TNSALP). This results in the inhibition of mineralization causing ...

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COHN Webinar: Medication-Related Osteonecrosis of the Jaw (MRONJ): An Update for the Dental Practitioner

The webinar is hosted by Dr. Tanya Gibson. The webinar explores the pathogenesis and risk factors of medication-related osteonecrosis of the jaw. As well, it looks at the recommended management strategies based on the clinical stage at the time of presentation. Participants will learn: the pathogenesis of MRONJ. risk factors for developing MRONJ. the clinical staging of MRONJ. management strategies for MRONJ. To register and attend the webinar, you can find more information here   Dr. Tanya Gibson DDS Tanya Marie Gibson, DDS, a native of Cleveland, Ohio, is an assistant professor at the University of Missouri Kansas City (UMKC) ...

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Premedication with Antimicrobials: Matching the Right Drug to the Right Bug!

Continuing our series of pharmacological topics, my conversation with Dr. Mark Donaldson was about premedication for dental procedures, in particular, about the management of orofacial infections with antimicrobials. It’s always a pleasure to host Dr. Donaldson on Oasis Discussions, and we hope that you will enjoy as well as benefit from this interview. I also would like to thank Dr. Donaldson for sharing the entire course with our viewers/readers.  Chiraz Guessaier, CDA Oasis Manager Resource Dr. Mark Donaldson: Premedication for Dental Procedures. Course Material. Please note that this material was initially developed for CE purposes. It is, however, presented here as ...

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Three Drug Classes Every Dental Professional Should Know!

It’s always an honour to meet with Dr. Mark Donaldson, Pharmacologist and senior Executive Director at Vizient Inc. Part of our monthly conversations, Mark spoke about the three drug classes that every dental professional should know: antimicrobials, analgesics, and local anesthetics. I hope you find the interview informative.  Chiraz Guessaier, CDA Oasis Manager Highlights Oral healthcare professionals (OHCPs) are routinely involved with the selection and prescription of medications for their patients. This course is designed to help them become better-informed prescribers of the top three drug classes employed in dentistry: antibiotics, analgesics, and local anesthetics. Patient safety is the number ...

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Oral Care in Cancer Therapy: Oral Care After Head & Neck Cancer Treatment

Drs. Deborah Saunders and Joel Epstein return to Oasis Discussions to discuss a third complication that occurs during cancer therapy and beyond, xerostomia. Xerostomia affects speech, chewing, swallowing, taste and overall nutrition which may negatively affect overall treatment and patient outcomes during therapy. Xerostomia is not related to aging as much as it reflects the use of medications that result in dry mouth. See also: Oral Care in Cancer Therapy Part 1: Oral Care Pre-Head & Neck Cancer TreatmentOral Care in Cancer Therapy Part 2: Oral Care During Cancer Therapy Functions of Saliva Antimicrobial activity Control of pH Removal of ...

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CE Showcase ASM2017: Fighting Dental Disease: Drugs, Bugs and Prescription Products

My interview with Dr. Peter Jacobsen went by in a flash! His sense of humor, light-delivery approach, and lively style leaves you glued to the screen, wanting to learn more about the topic presented. Dr. Jacobsen joined me to speak about his upcoming lecture at #ASM150 titled: Fighting Dental Disease: Drugs, Bugs and Prescription Products. Chiraz Guessaier, CDA Oasis Manager Highlights What are the first, second, third drugs of choice for dental infections? Which antifungals have the greatest risk of drug interactions? Are OTC aphthous ulcers medications effective? Can the newest antiviral drugs prevent herpes attacks? Do they put Ginkgo Biloba ...

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Oral Care in Cancer Therapy: Oral Care During Cancer Therapy

This second segment of the six-part series of oral complications in cancer treatment deals with fungal infections, most commonly candidiasis. See also: Oral Care in Cancer Therapy Part 1: Oral Care Pre-Head & Neck Cancer TreatmentOral Care in Cancer Therapy Part 3: Oral Care During Cancer Therapy Candidiasis or condidosis is an overgrowth of a commensal organism. The infection usually involves C. albicans, but C. krusei, dublinensis and torolopsilosis are also seen. It is important to note that resistance has been noted to medications by Candida spp. Etiology Due to systemic immune effects Extremes of age Malnutrition Cytotoxic CT Immune T-cell defects (HIV, ...

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Oral Care in Cancer Therapy: Oral Care Pre-Head & Neck Cancer Treatment

Drs. Deborah Saunders and Joel Epstein return to Oasis Discussions to discuss oral care before, during and after head and neck cancer treatment. See also: Oral Care in Cancer Therapy Part 2: Oral Care During Cancer TherapyOral Care in Cancer Therapy Part 3: Oral Care After Head & Neck Cancer Treatment Cancer is the leading cause of mortality in the world and it is expected to continue to grow. Infection-related cancers such as HPV, EBV and HCV are expected to play an important role in this increase. It is forecasted that a dentist will see ~1.3 newly diagnosed case of ...

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