My interview with Dr. Michaell Huber served as a review of the current status and of the latest in the area of adjunctive diagnostic techniques for diagnosing and discovering oral and oropharyngeal cancer. Dr. Huber is Professor and specialist in oral medicine in the Department of Comprehensive Dentistry at UT Health San Antonio Dental School. He authored an article in the Dental Clinics of North America titled: Adjunctive Diagnostic Techniques to diagnose Oral and Oropharyngeal Cancer. I hope you find the information valuable and enjoy the conversation. Please share your thoughts, questions, and suggestions with us at oasisdiscussions@cda-adc.ca Until next time! ...

In December 2017, the Journal of the American Dental Association (JADA) published an article on guidelines for preventive dental care. In it, the authors attempted to bridge a perceived knowledge gap through the development of a clinical registry of dental outcomes in head and neck cancer patients.  Dr. Bob Wood, oral radiologist and forensic dentist at Princess Margaret Cancer Center, suggests that the article needs a careful interpretation and an appropriate contextualization of the individualized treatment provided to these patients.  I hope you find the information beneficial and you will share your thoughts, suggestions, and questions with us through oasisdiscussions@cda-adc.ca ...

In this post, we present an Oasis Critical Moment, a crossroad moment that arise every day in clinical practice and where the decision the practitioner takes, can make the difference between grief for him/her and the patient, or comfort for all concerned.  We have invited Dr. Bob Wood and Dr. Erin Watson to guide the management of this case. Dr. Bob Wood is an oral radiologist and forensic dentist; and Dr. Erin Watson is a general dentist, and they both practice out of Princess Margaret Cancer Center in Toronto.  Imagine this scenario You are performing a fairly routine denture try-in ...

Today, we bring you two interesting complex cases that were treated by Dr. Erin Watson, general dentist practicing out of Princess Margaret Cancer Center, and Dr. Irwin Golosky, Endodontist in Toronto.  Both cases deal with patients who are at higher risk for medication related osteonecrosis of the jaw (MRONJ). Educational information is also presented to frame the situation and provide relevance to the general dentist. In cases where it is possible to prevent MRONJ, treatment is somewhat straightforward. However, in other cases where there is already a risk of MRONJ, treatment is challenging and requires the tight collaboration of a ...

Dr. Sheena Ramsey, Clinical Senior Lecturer in the Institute of Health and Society at Newcastle University, is the coauthor of a study that looked into identifying the link between poor oral health and physical frailty in a group of older British men. Although the link between poor oral health and good levels of nutrition seems obvious, it is important to seek evidence that proves such association. The cross-sectional and longitudinal study they conducted followed a cohort of older British men as part of the British Regional Heart Study. As usual, our hope is that the content is beneficial to you ...

On November 13th, 2017, the American Heart Association and the American College of Cardiology issued the first comprehensive new high blood pressure guidelines in more than a decade. To give us more details on the evidence behind this update to the guidelines, we invited Dr. Joaquin Cigarroa, a member of the joint American Heart Association and the American College of Cardiology task force that developed and drafted these new guidelines.  I hope you enjoy the interview informative and find the PDF resource valuable. Please share your feedback, suggestions, and questions through oasisdiscussions@cda-adc.ca Until next time! Chiraz Guessaier, CDA Oasis Manager Highlights ...

Highlights What is IRF6 and why was it important for you to look into this gene’s activity? The IRF6 gene is arguably one of the most significant contributors to the incidence of, and susceptibility to, cleft lip / palate. It encodes a protein, called a transcription factor, that functions in the nucleus of cells to turn on other genes. It primarily functions in epithelia, particularly in the developing embryo. It is a member of a small family of proteins, called interferon regulatory factors, that also have a role in immunity. What was the underlying theory of your research and how did you ...

Highlights Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation of oral dryness), and subjective sialorrhea cause significant morbidity and impair quality of life. However, no evidence-based lists of the medications that cause these disorders exist. The objective was to compile a list of medications affecting salivary gland function and inducing xerostomia or subjective sialorrhea. Data Sources Electronic databases were searched for relevant articles published until June 2013. Of 3867 screened records, 269 had an acceptable degree of relevance, quality of methodology, and strength of evidence. We found 56 chemical substances with a higher level of evidence and 50 with a moderate ...