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Oncology

What are the effects of different interventions used in the management of TMJ DDwoR? A systematic review

This summary is based on the article published in the Journal of Dental Research: TMJ Disc Displacement without Reduction Management: A Systematic Review (2014)

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How viable are titanium implants placed in irradiated jaws? A systematic review

This summary is based on the clinical review published in the Clinical Research Supplement of the Journal of Dental Research: Dental Implants Installed in Irradiated Jaws: A Systematic Review (December 2013)

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Does numbness matter? A clinical review of trigeminal neuropathy

This summary is based on the article published in Cephalagia: Numbness matters: A clinical review of trigeminal neuropathy (July 2011)

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How Frequent are Odontogenic Cysts and Tumours? A Systematic Review

This summary is based on the article published in the Journal of Investigative and Clinical Dentistry: Frequency of odontogenic cysts and tumors: a systematic review (February 2014) Nigel R. Johnson, Orla M. Gannon, Neil W. Savage, Martin D. Batstone For the next 3 months, you can access the full-text article (PDF). Courtesy of Wiley Publishing.

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Orofacial syndromes: a better understanding of the etiopathogenesis, diagnosis and management

This summary is based on the article published by the International Journal of Oral and Maxillofacial Pathology: Orofacial Syndromes: An Approach Towards Etiopathogenesis, Diagnosis and Management. A Systematic Review (January 2013) Context Currently, there are more than 4,000 genetic disorders identified to date, of which orofacial syndromes form a considerable part. Genetic factors either in isolation or in combination with various environmental factors play an important role in causing these craniofacial anomalies.  It becomes a challenge for the dental practitioner to diagnose and manage orofacial syndromes due to the complexity of their multi-system involvement.  Purpose of the Review The paper ...

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How efficient are Toluidine Blue and Brush Biopsy in diagnosing oral lesions?

This summary is based on the article published in the International Journal of Oral and Maxillofacial Pathology: Efficacy of Toluidine Blue and Brush Biopsy in Oral Lesions (January 2013) Context Oral cancer is a global health problem and its early detection is of prime importance. In vivo stains and brush biopsy have emerged in recent years to aid as clinical diagnostic tools.  Purpose of the Study The study assessed the efficacy and accuracy of Toluidine blue and brush biopsy in comparison to wedge biopsy in patients with oral pre-malignancies and malignant lesions.  Key Messages The combined evaluation of Toluidine blue ...

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What are the clinical considerations for dental implant therapy in irradiated head and neck cancer patients?

This summary is based on the article published in the Journal of Prosthodontics: Updated Clinical Considerations for Dental Implant Therapy in Irradiated Head and Neck Cancer Patients (August 2013) Context An increasing number of reports indicate successful use of dental implants (DI) during oral rehabilitation for head and neck cancer patients undergoing tumor surgery and radiation therapy. Implant-supported dentures are a viable option when patients cannot use conventional dentures due to adverse effects of radiation therapy, including oral dryness or fragile mucosa, in addition to compromised anatomy. However, negative effects of radiation, including osteoradionecrosis, are well documented in the literature, and early loss of implants in irradiated ...

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How do you manage a patient undergoing an allogeneic bone marrow transplant?

This question was submitted to us by a general dentist: How should we manage a patient undergoing an allogeneic bone marrow transplant? Dr. Jeff Chadwick, at Princess Margaret Cancer Centre, Dental Oncology, Ocular, and Maxillofacial Prosthetics Group, provided a preliminary response to this question The allogeneic bone marrow transplant (BMT) is a medical procedure that may be employed for the treatment of several hematologic malignancies including, but not limited to, aplastic anemia, myelodysplastic syndrome, acute and chronic leukemias and lymphomas. BMTs typically involve the insertion of a central venous catheter (CVC), high dose chemotherapy and, in some cases, total body irradiation, prior ...

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