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Medically Compromised Patients

What is Hypophosphatasia (HPP)?

Highlights In the first segment of a 4-part series, Dr. Marc McKee introduces Oasis Discussions followers to a soft bone disease which also has a significant dental impact. Hypophosphatasia (HPP) is a very rare disease that has a prevalence of  approximately 1:100,000 live births.  Much progress has been made in recent years in understanding HPP, and in treating patients with this condition. HPP is a disease which negatively affects mineralization due to an increase in inhibitory pyrophosphate levels caused by decreased activity of an enzyme called tissue non-specific alkaline phosphatase (TNAP, TNSALP). This results in the inhibition of mineralization causing ...

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COHN Webinar: Medication-Related Osteonecrosis of the Jaw (MRONJ): An Update for the Dental Practitioner

The webinar is hosted by Dr. Tanya Gibson. The webinar explores the pathogenesis and risk factors of medication-related osteonecrosis of the jaw. As well, it looks at the recommended management strategies based on the clinical stage at the time of presentation. Participants will learn: the pathogenesis of MRONJ. risk factors for developing MRONJ. the clinical staging of MRONJ. management strategies for MRONJ. To register and attend the webinar, you can find more information here   Dr. Tanya Gibson DDS Tanya Marie Gibson, DDS, a native of Cleveland, Ohio, is an assistant professor at the University of Missouri Kansas City (UMKC) ...

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Oral Care in Cancer Therapy: Oral Care After Head & Neck Cancer Treatment

Drs. Deborah Saunders and Joel Epstein return to Oasis Discussions to discuss a third complication that occurs during cancer therapy and beyond, xerostomia. Xerostomia affects speech, chewing, swallowing, taste and overall nutrition which may negatively affect overall treatment and patient outcomes during therapy. Xerostomia is not related to aging as much as it reflects the use of medications that result in dry mouth. See also: Oral Care in Cancer Therapy Part 1: Oral Care Pre-Head & Neck Cancer TreatmentOral Care in Cancer Therapy Part 2: Oral Care During Cancer Therapy Functions of Saliva Antimicrobial activity Control of pH Removal of ...

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Oral Care in Cancer Therapy: Oral Care During Cancer Therapy

This second segment of the six-part series of oral complications in cancer treatment deals with fungal infections, most commonly candidiasis. See also: Oral Care in Cancer Therapy Part 1: Oral Care Pre-Head & Neck Cancer TreatmentOral Care in Cancer Therapy Part 3: Oral Care During Cancer Therapy Candidiasis or condidosis is an overgrowth of a commensal organism. The infection usually involves C. albicans, but C. krusei, dublinensis and torolopsilosis are also seen. It is important to note that resistance has been noted to medications by Candida spp. Etiology Due to systemic immune effects Extremes of age Malnutrition Cytotoxic CT Immune T-cell defects (HIV, ...

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Oral Care in Cancer Therapy: Oral Care Pre-Head & Neck Cancer Treatment

Drs. Deborah Saunders and Joel Epstein return to Oasis Discussions to discuss oral care before, during and after head and neck cancer treatment. See also: Oral Care in Cancer Therapy Part 2: Oral Care During Cancer TherapyOral Care in Cancer Therapy Part 3: Oral Care After Head & Neck Cancer Treatment Cancer is the leading cause of mortality in the world and it is expected to continue to grow. Infection-related cancers such as HPV, EBV and HCV are expected to play an important role in this increase. It is forecasted that a dentist will see ~1.3 newly diagnosed case of ...

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CE Showcase ASM 2017: Medical Emergencies in the Dental Office – Medical Emergencies in Life!

It was a pleasure to meet and speak with Dr. Mel Hawkins for this interview. Generously, he prepared these slides to tell our audience what his session on medical emergencies will be about during ASM 2017. I hope you enjoy the conversation. Chiraz Guessaier, CDA Oasis Manager Highlights Dentists are treating an aging and pharmacologically drug dependent and ambulatory population. How can they be expected to respond/react to life-threatening situations when they “almost never occur” – or do they? Simplicity! Practical equipment adjuncts, a few good drugs, “red flags,” and understanding vasoconstrictor interactions, local anesthetic maximum doses, especially related to ...

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Craniofacial Implications of Osteogenesis Imperfecta

I had the pleasure to speak with Dr. Jean-Marc Retrouvey and view his presentation on the craniofacial implications of osteogenesis imperfecta. This is a disease that causes weak bones that break easily. It is also known as brittle bone disease where bones sometimes break for no known reason. OI can also cause many other problems, such as weak muscles, brittle teeth, and hearing loss. Dr. Retrouvey delved into the implications of treating patients that suffer from OI and what the possible treatments are. Chiraz Guessaier, CDA Oasis Manager Highlights Dr. Jean-Marc Retrouvey presents various craniofacial aspects of osteogenesis imperfecta. This is ...

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Local Anesthetics for the Patient Suffering from Methemoglobinemia

Dr. Joonyoung Ji speaks with Dr. John O’Keefe about the risks of administering local anesthetics to patients suffering from methemoglobinemia. Highlights Scenario A patient has a scope performed in a hospital setting and benzocaine was used to numb the area before inserting the scope. Subsequently, the patient developed methemoglobinemia. The patient’s physician has now advised that all “-caine-type” anesthetics must be avoided in this patient for all dental work. Management Context is important to determine why a scope was performed and how the situation that developed was managed. Often, in medical settings the amounts of local anesthetics that are used ...

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