Medicine

Featured debbie

Hypophosphatasia: Advocating for the Patient

In the last of four segments dedicated to hypophosphatasia (HPP), Debbie Taillefer, President and Founder, Soft Bones Canada, speaks to Dr. Suham Alexander about the importance of creating a community and patient advocacy forum for patients afflicted with soft bone diseases. Highlights Soft Bones Canada was created to fill the void that Debbie and other patients required when they were newly diagnosed with HPP. Soft Bones Canada works to help support and educate patients as well as to bridge the gap with medical professionals. Dentists can play an important role in early diagnosis of the disease since the earliest signs ...

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featured bob

Hypophosphatasia: A General Dentist’s Experience

Dr. Suham Alexander speaks to Dr. Bob Schroth in this third segment about hypophosphatasia (HPP) and the dental implications and management of patients with this condition. Children with HPP have some definite dental challenges. The developing teeth in these children lack cementum on the roots which leads to premature exfoliation. Additionally, large pulp chambers and irregular dentin and enamel defects increase the extent and risk of caries development. Radiographic tell-tale signs in HPP include: enlarged pulp horns, lower bone height interproximally as well as bony defects. Prudent use of dental radiographs is recommended in these patients as determined on a ...

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Featured Cheryl

The Genetic Foundation of Hypophosphatasia

Dr. Cheryl Greenberg, a pediatrician and geneticist, speaks to Dr. Suham Alexander about the clinical history and manifestations of HPP in her unique patient population in Winnipeg, MB. HPP is over-represented in the Mennonite population in Manitoba due to a “founder” mutation. Highlights HPP is categorized by age of onset: perinatal, infant, juvenile, adult (systemic forms) and odonto-hypophosphatasia (dental form). All patients with HPP must have a low level of alkaline phosphatase. There is a strong genetic basis for the various forms of HPP. There are more than 300 mutations described in the literature. However, one gene is responsible for ...

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Featured Aviv

Drug Therapy During Pregnancy with Dr. Aviv Ouanounou

Dr. Aviv Ouanounou returns to Oasis Discussions to speak about drug therapy during pregnancy. This presentation is based on an article authored by Drs. Aviv Ouanounou and Dan Haas, from the University of Toronto, in the British Dental Journal in 2016. The article was also selected by the Royal College of Dental Surgeons of Ontario as a Practice Enhancement and Knowledge (PEAK*) resource for Ontario dentists. *The goal of PEAK is to provide Ontario dentists with key articles on a wide-range of clinical and non-clinical topics from dental literature around the world. Highlights Pregnancy is a special time in a ...

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featured Marc 2

What is Hypophosphatasia (HPP)?

Highlights In the first segment of a 4-part series, Dr. Marc McKee introduces Oasis Discussions followers to a soft bone disease which also has a significant dental impact. Hypophosphatasia (HPP) is a very rare disease that has a prevalence of  approximately 1:100,000 live births.  Much progress has been made in recent years in understanding HPP, and in treating patients with this condition. HPP is a disease which negatively affects mineralization due to an increase in inhibitory pyrophosphate levels caused by decreased activity of an enzyme called tissue non-specific alkaline phosphatase (TNAP, TNSALP). This results in the inhibition of mineralization causing ...

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Featured tanya

COHN Webinar: Medication-Related Osteonecrosis of the Jaw (MRONJ): An Update for the Dental Practitioner

The webinar is hosted by Dr. Tanya Gibson. The webinar explores the pathogenesis and risk factors of medication-related osteonecrosis of the jaw. As well, it looks at the recommended management strategies based on the clinical stage at the time of presentation. Participants will learn: the pathogenesis of MRONJ. risk factors for developing MRONJ. the clinical staging of MRONJ. management strategies for MRONJ. To register and attend the webinar, you can find more information here   Dr. Tanya Gibson DDS Tanya Marie Gibson, DDS, a native of Cleveland, Ohio, is an assistant professor at the University of Missouri Kansas City (UMKC) ...

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Featured Mark

Premedication with Antimicrobials: Matching the Right Drug to the Right Bug!

Continuing our series of pharmacological topics, my conversation with Dr. Mark Donaldson was about premedication for dental procedures, in particular, about the management of orofacial infections with antimicrobials. It’s always a pleasure to host Dr. Donaldson on Oasis Discussions, and we hope that you will enjoy as well as benefit from this interview. I also would like to thank Dr. Donaldson for sharing the entire course with our viewers/readers.  Chiraz Guessaier, CDA Oasis Manager Resource Dr. Mark Donaldson: Premedication for Dental Procedures. Course Material. Please note that this material was initially developed for CE purposes. It is, however, presented here as ...

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Featured Mark

Three Drug Classes Every Dental Professional Should Know!

It’s always an honour to meet with Dr. Mark Donaldson, Pharmacologist and senior Executive Director at Vizient Inc. Part of our monthly conversations, Mark spoke about the three drug classes that every dental professional should know: antimicrobials, analgesics, and local anesthetics. I hope you find the interview informative.  Chiraz Guessaier, CDA Oasis Manager Highlights Oral healthcare professionals (OHCPs) are routinely involved with the selection and prescription of medications for their patients. This course is designed to help them become better-informed prescribers of the top three drug classes employed in dentistry: antibiotics, analgesics, and local anesthetics. Patient safety is the number ...

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