This case was submitted by a team of dental faculty members in the Oral Medicine and Pathology departments of the University of Pennsylvania School of Dental Medicine.
- Alicia M. Houston, D.D.S. (Resident – Department of Oral Medicine)
- Faizan Alawi, D.D.S. (Associate Professor of Pathology – Department of Pathology)
- Eric T. Stoopler, D.M.D., FDS, RCSEd, FDS RCSEng (Associate Professor of Oral Medicine)
- Case was edited by Dr. Suham Alexander, Oasis Clinical Editor
- Extraoral – NSF
- Intraoral – 2x2cm ulceration at R posterior lateral border of the tongue with indurated borders
- No herpes simplex virus found in direct fluorescent assay of lesion
Re-analysis of previous biopsy of the lesion reveals mucosal ulceration extending deep into the underlying regional skeletal muscle tissue (Figure 2).
Histopathology reveals dense mixed inflammatory infiltrate of lymphocytes, plasma cells, large mononuclear cells include histiocytes and numerous eosinophils (Figure 3).
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