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How effective are antimicrobial solutions?


bigstock-Mouthwash-Bottle-4391805This summary is based on the article published in Australian Endodontic Journal: Evaluation of the antimicrobial activities of chlorhexidine gluconate, sodium hypochlorite and octenidine hydrochloride in vitro (April 2013)

Purpose of the study

Compare the antimicrobial activity of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX) and octenidine hydrochloride (OCT) in different concentrations against endodontic pathogens in vitro


Agar diffusion procedure was used to determine the antimicrobial activity of the tested materials. Enterococcus faecalis, Candida albicans and the mixture of these were used for this study. In the agar diffusion test, 5.25% NaOCl exhibited better antimicrobial effect than the other concentrations of NaOCl for all strains.


All concentrations of OCT were effective against C. albicans and E. faecalis. Some 0.2% CHX was ineffective on all microorganisms. Antibacterial effectiveness of all experimental solutions decreased on the mixture of all strains. Decreasing concentrations of NaOCl resulted in significantly reduced antimicrobial effect.


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1 Comment

  1. JCDA Oasis September 6, 2013

    On behalf of Dr. Gary Ford: Since OCT seems better than CHX, it is available and/or recommended as an oral rinse agent? …and under what name can it be purchased?


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