How do I treat a patient with hemophilia?
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Hemophilia is a hereditary bleeding disorder caused by low factor VIII coagulant activity (hemophilia A) or low levels of factor IX coagulant activity (hemophilia B). Both forms have an X-linked recessive pattern of inheritance. Men are usually affected. Women are carriers.
Hemophilia Severity Classification
- Mild: No spontaneous bleeding; delayed onset of bleeding after trauma, surgery, or dental extractions (6%–49% of the normal clotting factor).
- Moderate: Bleeding with minor trauma; excessive bleeding with surgery (1%–5% of the normal clotting factor).
- Severe: Spontaneous bleeding; excessive bleeding with trauma or surgery (< 1% of the normal clotting factor).
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