How safe are benzodiazepines?
This summary is based on the Rapid Response Report developed by the Canadian Agency for Drugs and Technologies in Health: High dose and watchful dosing of benzodiazepines: a review of the safety and guidelines
- No “watchful dose” for benzodiazepines was identified.
- Benzodiazepines may be used in higher than 10 mg diazepam-equivalent doses in some circumstances, but data were limited.
- What is the clinical evidence for safety of high-dose (>10 mg diazepam equivalent) benzodiazepine use?
- What is the clinical evidence regarding the safety of different watchful doses of benzodiazepines?
- What are the evidence-based guidelines regarding watchful dosing or high-dose of benzdiazepines?
The JCDA Oasis Team is collaborating with the Canadian Agency for Drugs and Technologies in Health to provide you with the latest clinical information.
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